Exemestane (Aromasin) CAS 107868-30-4

Exemestane Usage and Dosage

Exemestane reaches peak plasma concentrations within 2 hours following the oral administration of a 25 mg dose. The active life of the drug is between 24 and 30 hours. This is significant since it is quite shorter than for the non-steroidal inhibitors. A single oral dose of 25 milligrams of exemestane causes a relatively long-lasting reduction in plasma and urinary estrogen levels, with maximal suppression occurring approximately 2 to 3 days after dosing and persists for about 4 to 5 days.

It has been shown that 25 milligrams of exemestane are basically just as effective as 50 milligrams at suppressing estrogen, raising testosterone levels, and levels of IGF. It is, therefore, unnecessary to go higher in doses than 25 milligrams per day. Due to the active life of the compound exemestane should be administered roughly once every twenty-four hours.